Really Cool Chemical Reaction Experiments You Can Easily Do at Home

These chemical reaction experiments are some of my favorite science activities for middle school.

When you hear the term chemical reaction, do you visualize something exploding? Most of us do. But not all reactions are that noticeable.

We’re actually surrounded by chemical change every day without thinking about it. Transformations like rust, a match lighting, yeast in bread, or silver tarnishing.

During our chemistry studies, we learned about different reactions by completing a bunch of fun hands-on projects like the ones listed below.

Kids making green elephant's toothpaste and tarnished pennies - chemical reaction experiments

Chemical Reaction Experiments

One of the best parts of teaching science at home is the fact that we get to add in as many experiments as we want. It’s important to schedule labs into your lesson plans because when science is interactive, kids have an easier time understanding the material.

Because we’re surrounded by chemical reactions all the time, it’s easy to study them.

Keep reading to see how you can inflate a balloon with baking soda and vinegar, grow crystals, create something that oozes, and lots more – all with different chemical reactions.

What is a Chemical Reaction

So what exactly is a chemical reaction? It is when a chemical change occurs.

The substances you start with react together and form something different. The reactants create a product. Bonds keeping atoms together are either broken or formed to create new molecules.

How do you know a chemical change has occurred? Look out for:

  • vaporization (production of gas)
  • precipitation (creation of a solid)
  • change in color
  • change in temperature
  • change in properties

In our science co-op, we learned about four types of reactions.


  • This is the simplest type of chemical reaction. It’s when two or more reactants are combined to create a more complex product.
  • A + B → AB


  • Decomposition is when a compound is broken down into its separate parts.
  • AB → A + B

Single replacement

  • This occurs when an element’s place in a compound is taken by another element.
  • A + BC → AC + B

Double replacement

  • In a double replacement, the ions in compounds are switched, creating a new compound.
  • AB + CD → AD + CB

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Baking Soda and Vinegar Balloon Experiment

What happens when you mix vinegar and baking soda in a balloon? Well, that’s what you’re going to find out during this lab.

This popular experiment may seem quite simple, but when you add in scientific questions, it makes it perfect for a middle school science lesson.

To make it super easy for your tweens to complete this baking soda and vinegar balloon lab, use these helpful printable worksheets.

You’ll need:

BalloonsBalloonsBalloonsBaking SodaBaking SodaBaking SodaDistilled White VinegarDistilled White VinegarDistilled White VinegarMeasuring SpoonsMeasuring SpoonsMeasuring SpoonsPlastic FunnelPlastic FunnelPlastic Funnel


  1. Using the funnel, add 3 TBSP of vinegar into the bottle.
  2. Dry off the funnel or grab a new one.
  3. Put the funnel into the balloon and add 1 tsp of baking soda into the balloon. Shake it so the powder falls into the large part of the balloon.
  4. Pull the funnel out of the balloon.
  5. Carefully, stretch the balloon over the bottle opening, making sure that the baking soda remains in the balloon.
  6. Lift up the balloon, letting the baking soda fall into the vinegar and watch the balloon inflate!

Some questions for your tweens to consider:

  • What do you think will happen?
  • What type of change took place?
  • What happened?
  • How long did the reaction continue?
Opt-in box for a science experiment. Worksheets for baking soda and vinegar balloon experiment.

Chemical Change Experiments

There are a number of activities you can do to at home that will physically show that a chemical change has occurred.

Add a couple of these labs to your science lessons to help your middle schooler understand the science behind chemical reactions.

Or use them as part of some summer science experiment fun over break for your middle schoolers!

Elephant Toothpaste Experiment

Kids get a kick out of seeing how hydrogen peroxide can be used to create something that oozes everywhere with this elephant toothpaste experiment.

Homemade Crystals

Use borax and pipe cleaners to grow your own crystals. While this shows you how to make crystal ornaments, you can actually make anything you’d like, just shape it from the pipe cleaner.

Foam Cup Meltdown Science Experiment

Foam cup meltdown! Show your kids how a foam cup melts when it comes in contact with acetone.

Lava Lamp Science Project

Making your own groovy lava lamp isn’t just a cool DIY project for tweens. It’s also a fun science experiment.

Supplies needed to make a DIY lava lamp for chemistry experiment

Penny Chemistry Experiment

In this clean penny experiment, tweens will tarnish some pennies to see how the copper reacts to oxygen and clean others to view how hydrogen chloride works with sodium acetate. Pretty cool penny chemistry.

Amazing Chemical Reactions

Check out 27 of the most amazing chemical reactions. Prepare to be blown away!

As you can see, there are a wide variety of safe and fun experiments you can do at home with your older kids to help them learn about chemical change as part of their chemistry studies. 

Boy pouring liquid into a test tube, causing a green chemical change.

Chemistry Experiments for Middle School

Here are some more chemistry experiments you can do at home with your tweens.

How to Teach Chemistry in a Fun Way

Use these helpful tools to make chemistry fun for your middle schoolers. They all make it easy to do science at home.

And don’t forget your printable worksheets – they’ll make it super easy to do a chemical change experiment at home using just baking soda, vinegar, and balloons!

What are your favorite chemical reaction experiments for middle school?

Megan Zechman
I love homeschooling! Learning is a way of life for our family. Most days you will find us exploring our Central Florida community, having fun while learning. I am constantly looking for new and interactive ways to engage my older children.
Megan Zechman
Megan Zechman
Megan Zechman

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  1. I LOVE this!!! I really like how you summarized the 4 types of reactions. We are covering chemistry come Jan and look forward to trying many of these ourselves.

    1. Thanks Eva! We’ve really been enjoying chemistry this year. We also spent some time balancing equations during our co-op. It was tricky, but they finally got it.

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